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Product Information:

HB007

HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader. HB007 induces ubiquitination and degradation of SUMO1, resulting in reduced tumor growth in vivo. HB007 can be used for the research of brain, breast, colon, and lung cancers.

Cat. No.: EX-A5607    Purity: >98%
Chemical
Chemical structure of HB007


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg700In-stock
100mg900In-stock
250mg1300In-stock
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CAS No.2387821-46-5
Purity>98%
FormulaC15H9ClN4OS
Mol Weight328.776
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Bellail AC, et, al. Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors. Sci Transl Med. 2021 Oct 13;13(615):eabh1486.

[2]. BELLAIL A, et, al. Compositions and methods for treating cancer. WO2019217509A1.
CoACoA of HB007

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