JND3229

JND3229 is a new highly potent EGFR(C797S) inhibitor with IC50 values of 5.8nM, 30.5nM and 6.8nM for EGFR (L858R/T790M/C797S), EGFR (T790M, L858R) and EGFR, respectively.


Cat. No.: EX-A3320	Purity: >98%

	Chemical structure of JND3229

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	550	In-stock
50mg	750	In-stock
100mg	1050	In-stock
250mg	1950	In-stock
1g	3900	Inquire
5g	14500	Inquire

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CAS No.	2260886-64-2
Purity	>98%
Formula	C33H41ClN8O2
Mol Weight	617.184
Appearance	Solid powder
Solubility	DMSO >10mg/mL (Need ultrasonic)
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lu X, et al. Discovery of JND3229 as a New EGFRC797S Mutant Inhibitor with In Vivo Monodrug Efficacy. ACS Med Chem Lett. 2018 Oct 8;9(11):1123-1127.
CoA	CoA of JND3229

Smiles:	CCC(=O)NC1CCC(CC1)N2C3=NC(=NC=C3CN(C2=O)C4=CC=CC=C4Cl)NC5=CC(=C(C=C5)N6CCN(CC6)C)C


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