ARV-110

ARV-110 (Bavdegalutamide) is an orally bioavailable, specific androgen receptor (AR) PROTAC degrader that leads to ubiquitination and degradation of AR.


Cat. No.: EX-A5017	Purity: >99%

	Chemical structure of ARV-110

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	325	In-stock
250mg	485	In-stock
500mg	685	In-stock
1g	985	In-stock
5g	2996	In-stock
10g	4872	In-stock

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Synonyms	Bavdegalutamide
CAS No.	2222112-77-6
Purity	>99%
Formula	C41H43ClFN9O6
Mol Weight	812.288
Appearance	Solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Neklesa T, et al. ARV-110: An oral androgen receptor PROTAC degrader for prostate cancer. Journal of Clinical Oncology. Journal of Clinical Oncology March 1 2019 37(7_suppl):259. [2]. Zeng S, et al. Proteolysis targeting chimera (PROTAC) in drug discovery paradigm: Recent progress and future challenges. Eur J Med Chem. 2021 Jan 15;210:112981. doi: 10.1016/j.ejmech.2020.112981. Epub 2020 Oct 31. PMID: 33160761. [3]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. doi: 10.1016/j.apsb.2019.08.001. Epub 2019 Aug 13. PMID: 32082969; PMCID: PMC7016280.
Data Sheet	Data sheet of ARV-110
CoA	CoA of ARV-110


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