LTGO-33

LTGO-33 is a potent and selective voltage-gated sodium channel NaV1.8 inhibitor. LTGO-33 inhibits NaV1.8 in the nM potency range and exhibits over 600-fold selectivity against human NaV1.1-NaV1.7 and NaV1.9.


Cat. No.: EX-A8588	Purity: >99%

	Chemical structure of LTGO-33

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	400	In-stock
100mg	650	In-stock
250mg	1150	In-stock
500mg	1885	In-stock
1g	get quote	In-stock
2g	get quote	In-stock

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CAS No.	2834106-06-6
Purity	>99%
Formula	C21H17F4N3O3S
Mol Weight	467.437
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Gilchrist JM, et al. Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel NaV1.8 with a Unique Mechanism of Action. Mol Pharmacol. 2024 Feb 15;105(3):233-249.
Data Sheet	Data sheet of LTGO-33
CoA	CoA of LTGO-33
SDS	SDS of LTGO-33

Smiles:	C(NC1=CC(S(C)(=N)=O)=CC=C1)(=O)C2=C(OC3=C(C)C=C(F)C=C3)N=CC(C(F)(F)F)=C2


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