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Product Information:

Arazasetron

Arazasetron (SENS-401) is an orally active calcineurin inhibitor. (R)-Azasetron besylate reduces Cisplatin-induced hearing loss and cochlear damage.

Cat. No.: EX-A8299    Purity: >98%
Chemical
Chemical structure of Arazasetron


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg550
100mg850
200mg1250
1g2500


SynonymsSENS-401
Synonyms 2(R)-Azasetron besylate
CAS No.2025360-91-0
Purity>98%
FormulaC23H26ClN3O6S
Mol Weight507.987
AppearanceSolid powder
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Petremann M, et al. SENS-401 Effectively Reduces Severe Acoustic Trauma-Induced Hearing Loss in Male Rats With Twice Daily Administration Delayed up to 96 hours. Otol Neurotol. 2019 Feb;40(2):254-263.

[2]. Petremann M, et al. Oral Administration of Clinical Stage Drug Candidate SENS-401 Effectively Reduces Cisplatin-induced Hearing Loss in Rats. Otol Neurotol. 2017 Oct;38(9):1355-1361.

CoACoA of Arazasetron
Smiles:O=S(O)(C1=CC=CC=C1)=O.O=C(C2=C(OCC(N3C)=O)C3=CC(Cl)=C2)N[C@H]4CN5CCC4CC5

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