MTK458

MTK458 is an orally active brain penetrant PINK1 activator. MTK458 binds to PINK1 and stabilizes an active heterocomplex, thereby increasing mitophagy. MTK458 can be used for research on Parkinson's disease.


Cat. No.: EX-A8247	Purity: >98%

	Chemical structure of MTK458

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	500	In-stock
250mg	900	In-stock
500mg	1400	In-stock
1g	2100	In-stock
2g	3300	In-stock
5g	5520	In-stock

Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670

Discount Request


Synonyms	EP-0035985
Synonyms 2	MTK-458
CAS No.	2499962-58-0
Purity	>98%
Formula	C17H15F3N4
Mol Weight	332.323
Appearance	White to light yellow solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Chin RM, et al. Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528378.
Data Sheet	Data sheet of MTK458
CoA	CoA of MTK458
SDS	SDS of MTK458


		Search