FAP-2286

FAP-2286 is a fibroblast activation protein (FAP)-binding peptidic macrocycle coupled to the radionuclide chelator DOTA. FAP-2286 has potent affinity to human FAP protein with a Kd of 1.1 nM. FAP-2286, a tumor imaging agent, is a useful tool for the research of positron emission tomography (PET). FAP-2286 has antitumor activity.


Cat. No.: EX-A7733	Purity: >98%

	Chemical structure of FAP-2286

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
1mg	685	In-stock
5mg	1385	In-stock
10mg	2185	In-stock
25mg	4000	In-stock
50mg	get quote	In-stock
100mg	get quote	In-stock

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CAS No.	2581741-18-4
Purity	>98%
Formula	C67H99N13O18S3
Mol Weight	1470.774
Appearance	solid powder
Solubility	soluble in water
Shelf Life	>2 years if stored properly
Storage	-20℃, protect from light, stored under nitrogen In solvent : -80℃, 6 months; -20℃, 1 month (protect from light, stored under nitrogen)
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Dirk Zboralski, et al. Comparative Biodistribution and Radiotherapeutic Efficacy of the Fibroblast Activation Protein (FAP)–Targeting Agents FAP-2286 and FAPI-46. [2]. Richard P Baum, et al. Feasibility, Biodistribution, and Preliminary Dosimetry in Peptide-Targeted Radionuclide Therapy of Diverse Adenocarcinomas Using 177 Lu-FAP-2286: First-in-Humans Results. J Nucl Med. 2022 Mar;63(3):415-423.
CoA	CoA of FAP-2286


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