RMC-9805

RMC-9805, a First-in-Class, Orally-Bioavailable, Tri-Complex Covalent KRAS-G12D(ON) Inhibitor, Drives Profound Anti-Tumor Activity in KRAS-G12D Mutant Tumor Models.


Cat. No.: EX-A7531	Purity: >98%

	Chemical structure of RMC-9805

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	200	In-stock
10mg	300	In-stock
100mg	1200	In-stock
500mg	3300	In-stock
1g	4900	In-stock

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Synonyms	Zoldonrasib
CAS No.	2922732-54-3
Purity	>98%
Formula	C63H88F3N11O7
Mol Weight	1168.4375
Appearance	white to off-white solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. John E. Knox, Jingjing Jiang, G. Leslie Burnett, Yang Liu, Caroline E. Weller, Zhican Wang, Laura McDowell, Shelby L. Steele, Shook Chin, Kang Jye Chou, Fang Wang, Mengqi Zhong, Elena S. Koltun, David Wildes, Mallika Singh, Adrian L. Gill, Jacqueline A. Smith; Abstract 3596: RM-036, a first-in-class, orally-bioavailable, Tri-Complex covalent KRASG12D(ON) inhibitor, drives profound anti-tumor activity in KRASG12D mutant tumor models. Cancer Res 15 June 2022; 82 (12_Supplement): 3596. https://doi.org/10.1158/1538-7445.AM2022-3596
CoA	CoA of RMC-9805


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