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Product Information:

LY2780301

LY2780301 is a potent, highly selective, ATP-competitive dual inhibitor of p70S6K and Akt under development for the treatment of solid tumours and non-Hodgkin's lymphoma.

Cat. No.: EX-A7418    Purity: >98%
Chemical
Chemical structure of LY2780301


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg685Inquire
50mg995Inquire
100mg1465Inquire
250mg2365Inquire
1g4850In-stock


CAS No.1226801-23-5
Purity>98%
FormulaC25H27F4N7O
Mol Weight517.5218
Appearancesolid powder
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Azaro, Analia et al. “A first-in-human phase I trial of LY2780301, a dual p70 S6 kinase and Akt Inhibitor, in patients with advanced or metastatic cancer.” Investigational new drugs vol. 33,3 (2015): 710-9.

[2]. Angevin, Eric et al. “Safety, tolerability and antitumour activity of LY2780301 (p70S6K/AKT inhibitor) in combination with gemcitabine in molecularly selected patients with advanced or metastatic cancer: a phase IB dose escalation study.” European journal of cancer (Oxford, England : 1990) vol. 83 (2017): 194-202.

CoACoA of LY2780301

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