background


Product Information:

MK-3118

MK-3118 (SCY-078, Ibrexafungerp), a glucan synthase inhibitor, is used potentially for the treatment of candida infection and aspergillosis.

Cat. No.: EX-A7291    Purity: >98%
Chemical
Chemical structure of MK-3118


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg780In-stock
25mg1500In-stock
100mg2800In-stock
250mg4900In-stock
500mgget quoteIn-stock
1gget quoteIn-stock


SynonymsSCY-078
Synonyms 2Ibrexafungerp
CAS No.1207753-03-4
Purity>98%
FormulaC44H67N5O4
Mol Weight730.0339
Appearancesolid powder
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lepak, Alexander J et al. “Pharmacodynamic target evaluation of a novel oral glucan synthase inhibitor, SCY-078 (MK-3118), using an in vivo murine invasive candidiasis model.” Antimicrobial agents and chemotherapy vol. 59,2 (2015): 1265-72.

[2]. Jiménez-Ortigosa, Cristina et al. “Enfumafungin derivative MK-3118 shows increased in vitro potency against clinical echinocandin-resistant Candida Species and Aspergillus species isolates.” Antimicrobial agents and chemotherapy vol. 58,2 (2014): 1248-51.

[3]. Pfaller, Michael A et al. “Activity of MK-3118, a new oral glucan synthase inhibitor, tested against Candida spp. by two international methods (CLSI and EUCAST).” The Journal of antimicrobial chemotherapy vol. 68,4 (2013): 858-63.

[4]. Pfaller, Michael A et al. “In vitro activity of a new oral glucan synthase inhibitor (MK-3118) tested against Aspergillus spp. by CLSI and EUCAST broth microdilution methods.” Antimicrobial agents and chemotherapy vol. 57,2 (2013): 1065-8.

CoACoA of MK-3118

KEYWORDS: buy MK-3118 | MK-3118 supplier | purchase | cost | manufacturer | order | distributor | buy 1207753-03-4 | 1207753-03-4 supplier