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Product Information:

AZD4831

Mitiperstat (AZD4831) is the potent inhibitor of myeloperoxidase (MPO). Mitiperstat is particularly useful in the research of prophylaxis of cardiovascular disorders such as heart failure and coronary artery disease related conditions (extracted from patent US20160152623A1).

Cat. No.: EX-A7129    Purity: >98%
Chemical
Chemical structure of AZD4831


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg450In-stock
50mg550In-stock
100mg700In-stock
250mg1200In-stock
500mg1900In-stock
1g3120In-stock


SynonymsMitiperstat
Synonyms 2AZD-4831
CAS No.1933460-19-5
Purity>98%
FormulaC15H15ClN4OS
Mol Weight334.824
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Tord Bertil INGHARDT, et al. 1-[2-(AMINOMETHYL)BENZYL]-2-THIOXO-1,2,3,5-TETRAHYDRO-4H-PYRROLO[3,2-d]PYRIMIDIN-4-ONES AS INHIBITORS OF MYELOPEROXIDASE. Patent US20160152623A1.

[2]. Lam, Carolyn S P et al. “Myeloperoxidase Inhibition in Heart Failure With Preserved or Mildly Reduced Ejection Fraction: SATELLITE Trial Results.” Journal of cardiac failure vol. 30,1 (2024): 104-110. doi:10.1016/j.cardfail.2023.04.003

[3]. Bhattacharya, Chandrali et al. “Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans.” Drug metabolism and disposition: the biological fate of chemicals vol. 51,4 (2023): 451-463. doi:10.1124/dmd.122.001100

Data SheetData sheet of AZD4831
CoACoA of AZD4831
SDSSDS of AZD4831

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