Product Information:
Cat. No.: EX-A656 | Purity: >98% |
Chemical structure of G007-LK |
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CAS No. | 1380672-07-0 |
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Purity | >98% |
Formula | C25H16ClN7O3S |
Mol Weight | 529.958 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Voronkov A, et al. Structural basis and SAR for G007-LK, a lead stage 1,2,4-triazole based specific tankyrase 1/2 inhibitor. J Med Chem, 2013, 56(7), 3012-3023.
[2]. Lau T, et al. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth. Cancer Res, 2013, 73(10), 3132-3144. |
CoA | CoA of G007-LK |
Smiles: | CS(=O)(=O)C1=CN=C(C=C1)C1=NN=C(\C=C\C2=NN=C(O2)C2=CC=C(C=C2)C#N)N1C1=CC=CC=C1Cl |
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