background


Product Information:

GDC-0214

iJak-381 (GDC-0214) is a highly potent, selective, and inhalable Janus kinase-1 (JAK-1) inhibitor which shows about 950 times higher concentration in the lungs than in plasma after inhalation in mice. iJak-381(GDC-0214) suppresses the signal transducer and activator of transcription 6 activation by IL-13.

Cat. No.: EX-A6434    Purity: >98%
Chemical
Chemical structure of GDC-0214


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
1g1885Inquire
2g2800Inquire
5g4800Inquire


SynonymsiJak-381
CAS No.1831144-46-7
Purity>98%
FormulaC28H28ClF2N9O3
Mol Weight612.03
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Dengler, Hart S et al. Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma. Science translational medicine vol. 10,468 (2018): eaao2151. doi:10.1126/scitranslmed.aao2151

CoACoA of GDC-0214

KEYWORDS: buy GDC-0214 | GDC-0214 supplier | purchase | cost | manufacturer | order | distributor | buy 1831144-46-7 | 1831144-46-7 supplier