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Product Information:

CL075

CL075 is a selective TLR8 agonist. CL075 induces production of TNF-α and IL-12 from peripheral blood mononuclear cells (PBMCs).

Cat. No.: EX-A5490    Purity: >98%
Chemical
Chemical structure of CL075


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg750Inquire
100mg950Inquire
200mg1350Inquire
500mg1950Inquire


CAS No.256922-53-9
Purity>98%
FormulaC13H13N3S
Mol Weight243.327
AppearanceOff-white Powder
SolubilitySoluble in DMSO and water
 
 
Reference:  [1]. Lai CY, et, al. TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7. Vaccine. 2014 Sep 29;32(43):5593-9.

[2]. Spranger S, et, al. Generation of Th1-polarizing dendritic cells using the TLR7/8 agonist CL075. J Immunol. 2010 Jul 1;185(1):738-47.
CoACoA of CL075

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