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Product Information:

FL118

FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2-induced resistance

Cat. No.: EX-A525    Purity: >98%
Chemical
Chemical structure of FL118


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg795In-stock
100mg1095In-stock
200mg1650In-stock
500mg2450In-stock


Synonyms10,11-Methylenedioxy-20(RS)-camptothecin
CAS No.151636-76-9
Purity>98%
FormulaC21H16N2O6
Mol Weight392.3615
Appearancefaint yellow solid
SolubilitySoluble in DMSO, not in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Westover et al. Molecular Cancer (2015) 14:92 DOI 10.1186/s12943-015-0362-9
CoACoA of FL118
Smiles:CCC1(O)C(=O)OCC2=C1C=C1N(CC3=C1N=C1C=C4OCOC4=CC1=C3)C2=O

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