K-975

K-975 is a first-in-class TEAD inhibitor, directly inhibiting YAP/TAZ-TEAD protein-protein interaction and showing a potent anti-tumor effect in malignant pleural mesothelioma.


Cat. No.: EX-A5112	Purity: >98%

	Chemical structure of K-975

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	300	In-stock
50mg	485	In-stock
100mg	750	In-stock
200mg	1185	In-stock

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CAS No.	2563855-03-6
Purity	>98%
Formula	C16H14ClNO2
Mol Weight	287.741
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kaneda A, et, al. The novel potent TEAD inhibitor, K-975, inhibits YAP1/TAZ-TEAD protein-protein interactions and exerts an anti-tumor effect on malignant pleural mesothelioma. Am J Cancer Res. 2020 Dec 1;10(12):4399-4415.
CoA	CoA of K-975

Smiles:	C=CC(NC1=CC=C(C)C(OC2=CC=C(Cl)C=C2)=C1)=O


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