Dac51

Dac51 is an FTO inhibitor. The FTO inhibitor Dac51 promotes T cell response and synergizes with anti-PD-L1 blockade. Dac51 can inhibit the activity of FTO.


Cat. No.: EX-A5100	Purity: >98%

	Chemical structure of Dac51

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	200	In-stock
25mg	350	In-stock
50mg	525	In-stock
100mg	800	In-stock
500mg	1885	In-stock
1g	3100	In-stock

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Synonyms	FTO-IN-1
Synonyms 2	FTO inhibitor 1
CAS No.	2243944-92-3
Purity	>98%
Formula	C18H16Cl2N4O2
Mol Weight	391.251
Appearance	Solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Liu Y, et al. Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance. Cell Metab. 2021; DOI:https://doi.org/10.1016/j.cmet.2021.04.001 [2]. WO 2018157843
CoA	CoA of Dac51

Smiles:	O=C(NO)C1=CC=CC=C1NC2=C(Cl)C=C(C3=C(C)NN=C3C)C=C2Cl


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