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Product Information:

AB-680

AB-680 is highly potent, reversible and selective small molecule inhibitor of CD73 (an ecto-nucleotidase), with a Ki of 4.9 pM for hCD73.

Cat. No.: EX-A4998    Purity: >98%
Chemical
Chemical structure of AB-680


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg950In-stock
250mg1685In-stock
1g3680In-stock
2gGet quoteIn-stock
3gGet quoteInquire
5gGet quoteInquire


SynonymsAB680
CAS No.2105904-82-1
Purity>98%
FormulaC20H24ClFN4O9P2
Mol Weight580.825
AppearanceSolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lawson KV, et al. Discovery and Characterization of AB680, a Potent and Selective Small-Molecule CD73 Inhibitor for Cancer Immunotherapy.

CoACoA of AB-680
Smiles:C[C@@H](C1=CC=CC=C1F)NC2=CC(=NC3=C2C=NN3[C@H]4[C@@H]([C@@H]([C@H](O4)COP(=O)(CP(=O)(O)O)O)O)O)Cl

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