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Product Information:

Mps1-IN-3 hydrochloride

Mps1-IN-3 hydrochloride is a potent and selective Mps1 inhibitor with an IC50 value of 50 nM. Mps1-IN-3 hydrochloride can inhibit the proliferation of glioblastoma cells, and effectively sensitizes glioblastomas to Vincristine in orthotopic glioblastoma xenograft model.

Cat. No.: EX-A4963A    Purity: >98%
Chemical
Chemical structure of Mps1-IN-3 hydrochloride


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
1g2200


CAS No.2989453-29-2
Purity>98%
FormulaC26H32ClN7O4S
Mol Weight574.095
 
 
Reference:  

[1]. Tannous BA, et al. Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs. J Natl Cancer Inst. 2013 Sep 4;105(17):1322-31.

CoACoA of Mps1-IN-3 hydrochloride
Smiles:OC1CCN(C2=CC=C(NC3=NC(NC4=CC=CC=C4S(=O)(C(C)C)=O)=C5N=CNC5=N3)C(OC)=C2)CC1.[H]Cl

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