Product Information:
Cat. No.: EX-A492 | Purity: >98% |
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Synonyms | Antibiotic C 15003P3 |
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Synonyms 2 | Maytansinol isobutyrate |
CAS No. | 66584-72-3 |
Purity | >98% |
Formula | C32H43ClN2O9 |
Mol Weight | 635.145 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Kiso T, et al. Screening for microtubule-disrupting antifungal agents by using a mitotic-arrest mutant of Aspergillus nidulans and novel action of phenylalanine derivatives accompanying tubulin loss. Antimicrob Agents Chemother. 2004 May;48(5):1739-48
[2]. Venghateri JB, et al. Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at thevinblastine site. PLoS One. 2013 Oct 4;8(10):e75182. |
CoA | CoA of Ansamitocin P-3 |
Smiles: | [H][C@@]12O[C@@]1(C)[C@H](CC(=O)N(C)C1=C(Cl)C(OC)=CC(C\C(C)=C\C=C\[C@@H](OC)[C@@]3(O)C[C@]([H])(OC(=O)N3)[C@H]2C)=C1)OC(=O)C(C)C |
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