AZ10606120 dihydrochloride

AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10 nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth.


Cat. No.: EX-A4666	Purity: >98%

	Chemical structure of AZ10606120 dihydrochloride

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	450	In-stock
1g	750	In-stock
5g	Get quote	In-stock

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CAS No.	607378-18-7
Purity	>98%
Formula	C25H36Cl2N4O2
Mol Weight	495.485
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Allsopp RC, et al. Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120. Sci Rep. 2017 Apr 7;7(1):725.
CoA	CoA of AZ10606120 dihydrochloride

Smiles:	O=C(NC1=C2C=CC(NCCNCCO)=NC2=CC=C1)CC3(C4)CC5CC4CC(C5)C3.[H]Cl.[H]Cl


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