Product Information:
Cat. No.: EX-A4656 | Purity: >98% |
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CAS No. | 1002304-34-8 |
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Purity | >98% |
Formula | C22H17N5O2 |
Mol Weight | 383.4027 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Albrecht BK, et al. Discovery and optimization of triazolopyridazines as potent and selective inhibitors of the c-Met kinase. J Med Chem. 2008, 51(10), 2879-2882.
[2]. Boezio AA, et al. Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors. Bioorg Med Chem Lett. 2009, 19(22), 6307-6312. [3]. Liu X, et al. Developing c-MET pathway inhibitors for cancer therapy: progress and challenges. Trends Mol Med. 2010,16(1), 37-45. |
CoA | CoA of AMG-208 |
Smiles: | COC1=CC2=NC=CC(=C2C=C1)OCC3=NN=C4N3N=C(C=C4)C5=CC=CC=C5 |
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