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Product Information:

KRAS inhibitor-9

KRAS inhibitor-9, a potent KRAS inhibitor (Kd=92 μM), blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 binds to KRAS G12D, KRAS G12C and KRAS Q61H protein with a moderate binding affinity. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 is KRAS inhibitor with potential antitumor activity. KRAS inhibitor-9 was reported in patent US 9884046.

Cat. No.: EX-A4387    Purity: >98%
Chemical
Chemical structure of KRAS inhibitor-9


For research only, Do not use for Human!

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CAS No.300809-71-6
Purity>98%
FormulaC13H9ClN2S2
Mol Weight292.807
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. patent US 9884046
CoACoA of KRAS inhibitor-9
Smiles:NC1=CC=C(SC2=NC3=CC=CC=C3S2)C(Cl)=C1

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