background


Product Information:

GSK3368715

GSK3368715 is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50s: 3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). It has strong anti-cancer activity.

Cat. No.: EX-A4367    Purity: >98%
Chemical
Chemical structure of GSK3368715


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
1gGet quote
5gGet quote


SynonymsGSK3368715 trihydrochloride
Synonyms 2EPZ019997
CAS No.1629013-22-4
Purity>98%
FormulaC20H38N4O2
Mol Weight366.5413
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Fedoriw A, et al. Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss. Cancer Cell. 2019 Jul 8;36(1):100-114.e25.

CoACoA of GSK3368715

KEYWORDS: buy GSK3368715 | GSK3368715 supplier | purchase | cost | manufacturer | order | distributor | buy 1629013-22-4 | 1629013-22-4 supplier