Product Information:
Cat. No.: EX-A4269 | Purity: >98% |
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CAS No. | 2057509-72-3 |
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Purity | >98% |
Formula | C22H28ClN5O2 |
Mol Weight | 429.943 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Bernard Barlaam, et al. Discovery of AZD4573, a potent and selective inhibitor of CDK9 that enables transient target engagement for the treatment of hematologic malignancies. AACR Cancer Res. 2018, 78(13 Suppl):Abstract nr 1650.
[2] Justin Cidado, et al. AZD4573, a novel CDK9 inhibitor, rapidly induces cell death in hematological tumor models through depletion of Mcl1. AACR Cancer Res. 2018, 78(13 Suppl):Abstract nr 310. |
CoA | CoA of AZD4573 |
Smiles: | ClC1=CN=C(NC([C@H]2CCC[C@@H](NC(C)=O)C2)=O)C=C1C3=C(CC(C)(C)C4)N4N=C3 |
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