Remibrutinib

Remibrutinib (LOU-064) is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.


Cat. No.: EX-A3421	Purity: >98%

	Chemical structure of Remibrutinib

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	600	In-stock
500mg	900	In-stock
1g	1450	In-stock
5g	4500	In-stock
10g	7200	In-stock
25g	Get quote	In-stock

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Synonyms	LOU-064
Synonyms 2	LOU064
CAS No.	1787294-07-8
Purity	>98%
Formula	C27H27F2N5O3
Mol Weight	507.5318
Appearance	solid powder
Solubility	Soluble in DMSO, not in water
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Daniela Angst, et al. Novel amino pyrimidine derivatives. Patent WO2015079417A1. [2]. Kolkhir P, et al. New treatments for chronic urticaria. Ann Allergy Asthma Immunol. 2019 Aug 23.
CoA	CoA of Remibrutinib

Smiles:	O=C(NC1=CC(F)=CC(C2=NC=NC(N)=C2OCCN(C)C(C=C)=O)=C1C)C3=CC=C(C4CC4)C=C3F


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