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Product Information:

SSM 3 trifluoroacetate

SSM3 tetraTFA is a potent synthetic furin inhibitor with an EC50 and a Ki of 54 nM and 12 nM, respectively. SSM3 tetraTFA is able to block furin-dependent cell surface processing of anthrax protective antigen-83 in vitro[1][2].

Cat. No.: EX-A15316    Purity: >98%
Chemical
Chemical structure of SSM 3 trifluoroacetate


For research only, Do not use for Human!

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CAS No.2320930-10-5
Purity>98%
FormulaC30H36F12N12O10
Mol Weight952.6621
 
 
Reference:  

[1]. Albert G Remacle, et al. Selective and Potent Furin Inhibitors Protect Cells From Anthrax Without Significant Toxicity. Int J Biochem Cell Biol

[2]. Guan-Sheng Jiao, et al. Synthetic Small Molecule Furin Inhibitors Derived From 2,5-dideoxystreptamine. Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19707-12.

CoACoA of SSM 3 trifluoroacetate
Smiles:C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=CC=C(C=C2)N=C(N)N)OC3=CC=C(C=C3)N=C(N)N)N=C(N)N.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O

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