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Product Information:

MBX-8025

Seladelpar (MBX-8025) is an orally active, potent (50% effect concentration EC50 2 nM), and specific PPAR-δ agonist.

Cat. No.: EX-A1512    Purity: >98%
Chemical
Chemical structure of MBX-8025


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg400In-stock
500mg585In-stock
1g785In-stock
5g2800In-stock
10g4680In-stock
25gGet quoteIn-stock


SynonymsSeladelpar
CAS No.851528-79-5
Purity>98%
FormulaC21H23F3O5S
Mol Weight444.465
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePure form -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Bays HE, et al. MBX-8025, a novel peroxisome proliferator receptor-delta agonist: lipid and other metabolic effects in dyslipidemic overweight patients treated with and without atorvastatin. J Clin Endocrinol Metab. 2011 Sep;96(9):2889-97.

[2]. Haczeyni F, et al. The selective peroxisome proliferator-activated receptor-delta agonist seladelpar reverses nonalcoholic steatohepatitis pathology by abrogating lipotoxicity in diabetic obese mice. Hepatol Commun. 2017 Jul 31;1(7):663-674.

CoACoA of MBX-8025
Smiles:CCO[C@H](COC1=CC=C(C=C1)C(F)(F)F)CSC1=CC=C(OCC(O)=O)C(C)=C1

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