Dovramilast

Dovramilast (CC-11050) is an orally active phosphodiesterase 4 (PDE4) inhibitor and can reduce the inflammatory response and improves Isoniazid (INH)-mediated bacillary clearance from the lungs. Dovramilast, as an adjunct, is used for the research of tuberculosis (TB).


Cat. No.: EX-A12042	Purity:

	Chemical structure of Dovramilast

For research only, Do not use for Human!

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Synonyms	CC-11050
CAS No.	340019-69-4
Formula	C24H28N2O6S
Mol Weight	472.554
Shelf Life	>3 years if stored properly
Storage	Powder 4℃,protect from light, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. International Nonproprietary Names for Pharmaceutical Substances (INN). WHO Drug Information, Vol. 36, No. 2, 2022. [2]. Selvakumar Subbian, et al. Pharmacologic Inhibition of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance of Mycobacterium tuberculosis. Front Immunol. 2016 Jun 17;7:238.
CoA	CoA of Dovramilast

Smiles:	N(C(=O)C1CC1)C2=C3C(CN([C@H](CS(C)(=O)=O)C4=CC(OCC)=C(OC)C=C4)C3=O)=CC=C2


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