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Product Information:

SHIN2

SHIN2 is a novel SHMT inhibitor, increasing survival in NOTCH1-driven mouse primary T-ALL in vivo.

Cat. No.: EX-A5815    Purity: >98%
Chemical
Chemical structure of SHIN2


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg400In-stock
50mg550In-stock
100mg700In-stock
250mg1250In-stock
500mg1950In-stock
1g2950In-stock


Synonyms(Rac)-SHIN2
Synonyms 2SHIN-2
CAS No.2204289-53-0
Purity>98%
FormulaC23H26N4O3
Mol Weight406.4775
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. García-Cañaveras, Juan C et al. “SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia.” Leukemia vol. 35,2 (2021): 377-388.

[2]. Mootha Vamsi, et al. Method of treating and preventing viral infection comprising inhibitors of folate or one-carbon metabolism pathways such as serine hydroxymethyltransferase inhibitors: World Intellectual Property Organization, WO2022120195[P]. 2022-06-09.

Data SheetData sheet of SHIN2
CoACoA of SHIN2
SDSSDS of SHIN2

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