Zuranolone

SAGE-217 is an investigational, oral, neuroactive steroid and GABAA receptor positive allosteric modulator that has demonstrated reductions in depressive symptoms in a Phase 2 double-blind, randomized, placebo-controlled study in MDD.


Cat. No.: EX-A1880	Purity: >98%

	Chemical structure of Zuranolone

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	785	In-stock
10mg	1085	In-stock
50mg	1950	In-stock
100mg	2950	In-stock

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Synonyms	SAGE-217
Synonyms 2	BIIB125
CAS No.	1632051-40-1
Purity	>98%
Formula	C25H35N3O2
Mol Weight	409.5643
Color	white
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Martinez Botella G, et al. Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one: A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)A Receptor. J Med Chem. 2017 Sep 28;60(18):7810-7819.
CoA	CoA of Zuranolone

Smiles:	[H][C@@]12CC[C@H](C(=O)CN3C=C(C=N3)C#N)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@](C)(O)CC[C@]12[H]


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