ZT55

ZT55 is an orally active and highly-selective JAK2 inhibitor with an IC50 value of 0.031 μM. ZT55 inhibits the proliferation of JAK2V617F-expressing HEL cell lines and induces apoptosis and cycle arrest.


Cat. No.: EX-A8410	Purity: >98%

	Chemical structure of ZT55

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
25mg	788	Inquire
1g	2880	Inquire

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CAS No.	2138488-38-5
Purity	>98%
Formula	C17H16N2O3
Mol Weight	296.3205
Color	White to off-white
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hu M, et al. Discovery and evaluation of ZT55, a novel highly-selective tyrosine kinase inhibitor of JAK2V617F against myeloproliferative neoplasms. J Exp Clin Cancer Res. 2019 Feb 4;38(1):49.
CoA	CoA of ZT55

Smiles:	O=C(NC1=CC=CC=C1OC)CC2=CN(O)C3=C2C=CC=C3


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