Zoniporide dihydrochloride

Zoniporide dihydrochloride (CP-597396 dihydrochloride) is a potent and selective inhibitor of highly water-soluble sodium hydrogen exchange type 1 (NHE-1). Zoniporide dihydrochloride inhibits NHE1 dependent 22Na+ uptake in vitro with an IC50 of 14 nM. Zoniporide has antitumor activity[1][2].


Cat. No.: EX-A15447	Purity: >98%

	Chemical structure of Zoniporide dihydrochloride

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
1g	792	inquire
5g	2480	inquire
10g	3212	inquire

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Synonyms	CP-597396 dihydrochloride
CAS No.	241799-10-0
Purity	>98%
Formula	C17H18Cl2N6O
Mol Weight	393.27
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Marala RB, et al. Zoniporide: a potent and highly selective inhibitor of human Na(+)/H(+) exchanger-1. Eur J Pharmacol. 2002 Sep 6;451(1):37-41. [2]. Sanhueza C, et al. Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer. Biochim Biophys Acta Mol Basis Dis. 2017 Jan;1863(1):81-91.
CoA	CoA of Zoniporide dihydrochloride

Smiles:	C1CC1C2=C(C=NN2C3=CC=CC4=C3C=CC=N4)C(=O)N=C(N)N.Cl.Cl


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