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Product Information:

Zoliflodacin

Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus with the MIC90 of 0.25 μg/mL.

Cat. No.: EX-A2620    Purity: >98%
Chemical
Chemical structure of Zoliflodacin


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg585In-stock
100mg750In-stock
250mg1250In-stock
500mg1900In-stock
1g2550In-stock
5gget quoteIn-stock


SynonymsAZD0914
Synonyms 2ETX0914
CAS No.1620458-09-4
Purity>98%
FormulaC22H22FN5O7
Mol Weight487.4378
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Huband MD, et al. In vitro antibacterial activity of AZD0914, a new spiropyrimidinetrione DNA gyrase/topoisomerase inhibitor with potent activity against Gram-positive, fastidious Gram-Negative, and atypical bacteria. Antimicrob Agents Chemother. 2015 Jan;59(1):467-74.

CoACoA of Zoliflodacin
Smiles:[H][C@]12[C@H](C)O[C@H](C)CN1C1=C(CC22C(=O)NC(=O)NC2=O)C=C2C(=NOC2=C1F)N1[C@@H](C)COC1=O

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