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Product Information:

ZA3-EP10

ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles (LNPs) formulation for in vivo RNA delivery and non-viral CRISPR/Cas Gene editing.

Cat. No.: EX-A5441    Purity: >98%
Chemical
Chemical structure of ZA3-EP10


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mgget quote
1gget quote


CAS No.2090299-48-0
Purity>98%
FormulaC66H138N6O9S
Mol Weight1191.902
ColorWhite to light yellow
StateOil
SolubilitySoluble in DMSO ? 100 mg/mL
Shelf Life>3 years if stored properly
StoragePure form 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Non-viral CRISPR/Cas gene editing in vitro and in vivo enabled by synthetic nanoparticule co-delivery of Cas9 mRNA and sgRNA. Miller, J.B. et al. Angew Chem Int Ed Engl. 56(4), 1059-1063, 2018; doi: 10.1002/anie.201610209

[2]. Strategies for CRISPR-based Therapeutics. Li, B. et al. Trends in Pharmacological Sciences, 41(1), 2020; doi: 10.1016/j.tips.2019.11.006

[3]. Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids. Siegwart, D.J.; Miller, J.B. WO2017201076A1
CoACoA of ZA3-EP10

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