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Product Information:

Z-VEID-FMK

Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a selective and irreversible caspase-6 peptide inhibitor. Z-VEID-FMK alleviates the S-(+)-ketamine-induced augmentation of caspase-6 activity, DNA fragmentation, and cell apoptosis.

Cat. No.: EX-A8881    Purity: >98%
Chemical
Chemical structure of Z-VEID-FMK


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg750In-stock
25mg1550In-stock
50mg2450In-stock
100mgget quoteIn-stock
250mgget quoteIn-stock
1gget quoteIn-stock


SynonymsZ-VE(OMe)ID(OMe)-FMK
CAS No.210344-96-0
Purity>98%
FormulaC31H45FN4O10
Mol Weight652.7082
Colorwhite to off-white
Statesolid
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. S-T Lee, et al. Apoptotic insults to human HepG2 cells induced by S-(+)-ketamine occurs through activation of a Bax-mitochondria-caspase protease pathway. Br J Anaesth. 2009 Jan;102(1):80-9.

[2]. Philippe P Monnier, et al. Involvement of caspase-6 and caspase-8 in neuronal apoptosis and the regenerative failure of injured retinal ganglion cells. J Neurosci. 2011 Jul 20;31(29):10494-505.

CoACoA of Z-VEID-FMK

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