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Product Information:

YT-8-8

YT-8-8 is a ligand of p62-ZZ domain. YT-8-8 can activate p62-dependent selective macroautophagy. YT-8-8 can be used for AUTOTAC design .

Cat. No.: EX-A9794    Purity: >98%
Chemical
Chemical structure of YT-8-8


For research only, Do not use for Human!

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CAS No.892572-23-5
Purity>98%
FormulaC18H23FN2O2
Mol Weight318.3858
ColorWhite to off-white
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4°C, stored under nitrogen, away from moisture; In solvent -20°C, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ji CH, et al. The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system. Nat Commun. 2022 Feb 16;13(1):904.

CoACoA of YT-8-8
Smiles:FC1=CC=C(C=C1)COC2=CC=CC(=C2)CNCCNCCO

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