YM-I-26

YM-I-26 is a selective NLRP3 inflammasome inhibitor. YM-I-26 enhances the phagocytosis of β-amyloid protein by mouse microglial BV2 cells and inhibits the production of IL-1β and IL-10. YM-I-26 can be used to study the immunomodulatory activity associated with inflammation .


Cat. No.: EX-A17343	Purity: >98%

	Chemical structure of YM-I-26

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	525	Inquire
10mg	685	Inquire
25mg	985	Inquire
100mg	1585	Inquire

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CAS No.	2585015-90-1
Purity	>98%
Formula	C28H33ClN2O5S2
Mol Weight	577.155

Reference:	[1].Biby S, et al. Functional Characterization of an Arylsulfonamide-Based Small-Molecule Inhibitor of the NLRP3 Inflammasome[J]. ACS Chemical Neuroscience, 2024.
CoA	CoA of YM-I-26

Smiles:	O=S(C1=CC=C(CCN(CC2=C(OCCC)C=CC(Cl)=C2)C(CC3=CSC=C3)=O)C=C1)(N4CCOCC4)=O


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