YLT-11

YLT-11 is a potent, selective and orally active PLK4 inhibitor with Kd values of >10000, 653, >10000, 5.2 nM for PLK1, PLK2, PLK3, PLK4, respectively. YLT-11 shows antiproliferative activity. YLT-11 induces Apoptosis and cell cycle arrest at G2/M phase. YLT-11 show anticancer activity.


Cat. No.: EX-A7583	Purity: >98%

	Chemical structure of YLT-11

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	get quote	enquire
1g	get quote	enquire
2g	get quote	enquire
3g	get quote	enquire
5g	get quote	enquire
10g	get quote	enquire

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


Purity	>98%
Formula	C24H24N6O
Mol Weight	412.487
Color	White to off-white
State	solid powder
Solubility	H2O : 50 mg/mL DMSO : 20 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lei Q, et al. YLT-11, a novel PLK4 inhibitor, inhibits human breast cancer growth via inducing maladjusted centriole duplication and mitotic defect. Cell Death Dis. 2018 Oct 18;9(11):1066.
CoA	CoA of YLT-11


		Search