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Product Information:

YKL-06-101

YKL-06-101 is a bivalent small molecule that combines mTOR inhibition (IC50=6 nM) and degradation of CDK8 (CDK8/Cyclin C IC50=31 nM).

Cat. No.: EX-A7947    Purity: >98%
Chemical
Chemical structure of YKL-06-101


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg3885Inquire


Purity>98%
FormulaC58H57F3N8O11
Mol Weight1099.1154
Statesolid powder
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Menzl, Ingeborg et al. “A kinase-independent role for CDK8 in BCR-ABL1+ leukemia.” Nature communications vol. 10,1 4741. 18 Oct. 2019

CoACoA of YKL-06-101

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