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Product Information:

XOR/URAT1-IN-1

XOR/URAT1-IN-1 (Compound II15) is a dual inhibitor for xanthine oxidoreductase (XOR) and uric acid transporter 1 (URAT1), with IC50 of 6 nM and 12.9 μM. XOR/URAT1-IN-1 lowers the levels of uric acid in Potassium oxonate/Hypoxanthine-induced acute hyperuricemia mouse model.

Cat. No.: EX-A13945    Purity: >98%
Chemical
Chemical structure of XOR/URAT1-IN-1


For research only, Do not use for Human!

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CAS No.2810137-86-9
Purity>98%
FormulaC18H13ClN2O3
Mol Weight340.76
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yang C, et al., Design, synthesis, and biological evaluation of 3-phenyl substituted pyridine derivatives as potential dual inhibitors of XOR and URAT1. Eur J Med Chem. 2024 May 5;271:116407.

CoACoA of XOR/URAT1-IN-1
Smiles:O=C(O)C=1C=CC(=CC1O)C2=CN=CC(=C2)NC=3C=CC=C(Cl)C3

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