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Product Information:

XO44

PF-6808472 (XO44) is a broad-spectrum covalent kinase probe. XO44 can bind in CDK2 and CDK1 .

Cat. No.: EX-A9773    Purity: >98%
Chemical
Chemical structure of XO44


For research only, Do not use for Human!

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50mg684In-stock
100mg1188In-stock
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SynonymsXO44
Synonyms 2PF-6808472
CAS No.2088112-70-1
Purity>98%
FormulaC25H27FN8O3S
Mol Weight538.597
ColorWhite to off-white
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Kevin D Freeman-Cook, et al. Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer. J Med Chem. 2021 Jul 8;64(13):9056-9077.

CoACoA of XO44
Smiles:O=S(C1=CC=C(CN2CCN(C3=NC(C(NCC#C)=O)=CC(NC4=NNC(C5CC5)=C4)=N3)CC2)C=C1)(F)=O

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