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Product Information:

XMD8-85

XMD8-85 (ERK5-IN-1) is a selective and potent inhibitor of ERK5 and LRRK2 with IC50s of 0.162 μM and 0.339 μM, respectively.

Cat. No.: EX-A3073    Purity: >98%
Chemical
Chemical structure of XMD8-85


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg725In-stock
250mg1125In-stock
1gget quoteIn-stock
custom sizget quote


SynonymsERK5-IN-1
CAS No.1234479-76-5
Purity>98%
FormulaC25H29N7O2
Mol Weight459.5435
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Deng, Xianming et al. “Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones. European journal of medicinal chemistry vol. 70 (2013): 758-67.

CoACoA of XMD8-85
Smiles:CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C5=CC=CC=C5C(=O)N4C)C)OC

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