XL-188

XL-188 is a potent, selective, non-covalent active-site inhibitor of USP7 with IC50 of 90 nM and 193 nM for USP7 full length enzyme and catalytic domain, respectively.


Cat. No.: EX-A6239	Purity: >98%

	Chemical structure of XL-188

For research only, Do not use for Human!

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Synonyms	XL 188
Synonyms 2	XL188
CAS No.	2305045-76-3
Purity	>98%
Formula	C32H42N6O4
Mol Weight	574.7137
Color	Off-white to light yellow
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Stolte B, et, al. Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma. J Exp Med. 2018 Aug 6;215(8):2137-2155.
CoA	CoA of XL-188


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