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Product Information:

Wu-5

Wu-5 is a novel USP10 inhibitor, enhances crenolanib-induced FLT3-ITD-positive AML cell death via inhibiting FLT3 and AMPK pathways.

Cat. No.: EX-A5824    Purity: >98%
Chemical
Chemical structure of Wu-5


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg750In-stock
50mg1050In-stock
100mg1600In-stock
200mg2550In-stock


CAS No.2630378-05-9
Purity>98%
FormulaC15H13NO7S
Mol Weight351.331
ColorOff-white to light yellow
Statesolid powder
SolubilitySoluble in DMSO 25 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Yu M, Fang ZX, Wang WW, Zhang Y, Bu ZL, Liu M, Xiao XH, Zhang ZL, Zhang XM, Cao Y, Wang YY, Lei H, Xu HZ, Wu YZ, Liu W, Wu YL. Wu-5, a novel USP10 inhibitor, enhances crenolanib-induced FLT3-ITD-positive AML cell death via inhibiting FLT3 and AMPK pathways. Acta Pharmacol Sin. 2021 Apr;42(4):604-612. doi: 10.1038/s41401-020-0455-x. Epub 2020 Jul 21. PMID: 32694757; PMCID: PMC8115260.
CoACoA of Wu-5

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