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Product Information:

WIZ degrader 4

WIZ degrader 4 (Example 1) is a WIZ degrader with an AC50 value of 160 nM. WIZ degrader 4 can be used to investigate sickle cell disease (SCD) and thalassemia.

Cat. No.: EX-A13372    Purity: >98%
Chemical
Chemical structure of WIZ degrader 4


For research only, Do not use for Human!

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CAS No.2879250-22-1
Purity>98%
FormulaC20H25N3O4
Mol Weight371.4302
ColorWhite to off-white
StateSolid
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years , 4°C, 2 years; In solvent -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Simone BONAZZI, et al. 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and medical uses thereof. WO2022254362A1.2022-12-08.

CoACoA of WIZ degrader 4
Smiles:CCN1CCC[C@H](C1)OC2=CC=C3C(N(CC3=C2)C4CCC(NC4=O)=O)=O

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