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Product Information:

WDR5-47

WDR5-MLL1 antagonist 1 (compound 47) is a compound optimized through protein crystal structure guidance. It has stronger antagonistic activity against WDR5-MLL interaction with a dissociation constant (Kd) of 0.3μM.

Cat. No.: EX-A7372    Purity: >98%
Chemical
Chemical structure of WDR5-47


For research only, Do not use for Human!

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CAS No.1422389-91-0
Purity>98%
FormulaC19H20ClFN4O3
Mol Weight406.839
ColorLight yellow to yellow
Statesolid powder
SolubilityDMSO : 20.83 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent    -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction

CoACoA of WDR5-47

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