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Product Information:
| Cat. No.: EX-A1759 | Purity: >99.5% HPLC |
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| Chemical structure of VX-661 |
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| Synonyms | Tezacaftor |
|---|---|
| CAS No. | 1152311-62-0 |
| Purity | >99.5% HPLC |
| Formula | C26H27F3N2O6 |
| Mol Weight | 520.4976 |
| State | solid powder |
| Solubility | DMSO >20mg/mL |
| Shelf Life | >2 years if stored properly |
| Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Reference: | [1]. S. Donaldson, J. Pilewski, M. Griese, Q. Dong, P.-S. Lee, for the VX11–661-101 Study Group. WS7.3 VX-661, an investigational CFTR corrector, in combination with ivacaftor, a CFTR potentiator, in patients with CF and homozygous for the F508Del-CFTR mutation: Interim analysis. Journal of Cystic Fibrosis, Volume 12, Supplement 1, June 2013, Page S14 |
| CoA | CoA of VX-661 |
| Smiles: | CC(C)(CO)C1=CC2=CC(NC(=O)C3(CC3)C3=CC4=C(OC(F)(F)O4)C=C3)=C(F)C=C2N1C[C@@H](O)CO |
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