VV116

Mindeudesivir (JT001; VV116; GS-621763-d1) hydrobromide is a deuterated version of Remdesivir (EX-A3265), a highly orally active nucleoside antiviral against SARS-CoV-2 and respiratory syncytial virus (RSV). Mindeudesivir hydrobromide retains the antiviral activity of Remdesivir against COVID-19, and is the first domestically produced deuterium targeting the COVID-19. VV116 free base please refer to EX-A5453A.


Cat. No.: EX-A5453	Purity: >98%

	Chemical structure of VV116

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	1075	In-stock
200mg	1575	In-stock
500mg	2175	In-stock
1g	3600	Inquire

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


Synonyms	Mindeudesivir hydrobromide
Synonyms 2	GS-621763-d1 hydrobromide
CAS No.	2779498-79-0
Purity	>98%
Formula	C24H32BrN5O7
Mol Weight	583.45
Color	White to light yellow
State	solid powder
Solubility	Soluble in DMSO 250 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Xie, Y., Yin, W., Zhang, Y. et al. Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2. Cell Res 31, 1212–1214 (2021). https://doi.org/10.1038/s41422-021-00570-1. [2]. Zhang R, et al. Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model. Signal Transduct Target Ther. 2022;7(1):123. Published 2022 Apr 16. [3]. Qian HJ, et al. Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects [published online ahead of print, 2022 Mar 16]. Acta Pharmacol Sin. 2022;1-9.
CoA	CoA of VV116


		Search