VU591

VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 can be used for neurological research with the equivalent of VU591 hydrochloride.


Cat. No.: EX-A11055	Purity: >98%

	Chemical structure of VU591

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	438	In-stock
500mg	632	In-stock
1g	885	In-stock
5g	2685	In-stock
10g	4585	In-stock

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CAS No.	1222810-74-3
Purity	>98%
Formula	C16H12N6O5
Mol Weight	368.3037
Color	Light yellow to yellow
State	Solid
Solubility	DMSO : 62.5 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Bhave G, et al. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol Pharmacol. 2011 Jan;79(1):42-50. [2]. Masayoshi Okada, et al. Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ. PLoS One. 2020 Nov 13;15(11):e0233815.
CoA	CoA of VU591

Smiles:	O=[N+]([O-])C1=CC(NC(COCC2=NC3=C(N2)C=C([N+]([O-])=O)C=C3)=N4)=C4C=C1


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